Spatial heterogeneity of T cell repertoire across NSCLC tumors, tumor edges, adjacent and distant lung tissues.
Qikang HuMeredith L FrankYang GaoLiyan JiMuyun PengChen ChenBin WangYan HuZeyu WuJina LiLu ShuQiongzhi HeYingqian ZhangXuefeng XiaJianjun ZhangXin YiAlexandre ReubenFenglei YuPublished in: Oncoimmunology (2023)
Exclusion in T exhaustion cells at play across the lungs of patients with NSCLC may potentially be the mechanism for lung cancer occurrence.
Keyphrases
- small cell lung cancer
- induced apoptosis
- advanced non small cell lung cancer
- cell cycle arrest
- risk assessment
- gene expression
- lymph node
- brain metastases
- single cell
- endoplasmic reticulum stress
- cell death
- oxidative stress
- signaling pathway
- cell proliferation
- epidermal growth factor receptor
- high throughput sequencing
- tyrosine kinase