Thrombosis pathways in COVID-19 vs. influenza-associated ARDS: A targeted proteomics approach.

Emma Rademaker Dennis J Doorduijn Nuray Kusadasi Coen Maas Julia Drylewicz Albert Huisman Imo E HoeferMarc J M BontenLennie P G Derde Suzan H M Rooijakkers Olaf L Cremer

Published in: Journal of thrombosis and haemostasis : JTH (2022)

We observed only minor differences between matched C19PE+, C19PE-, and IAA patients, which suggests individual biomarkers mostly reflect disease severity. However, analysis of total pathway activity suggested upregulation of some distinct processes in COVID-19 could be etiologically related to increased PE-risk.

Keyphrases

coronavirus disease
sars cov
end stage renal disease
newly diagnosed
chronic kidney disease
mass spectrometry
prognostic factors
pulmonary embolism
extracorporeal membrane oxygenation
acute respiratory distress syndrome
peritoneal dialysis
signaling pathway
drug delivery
drug induced