Estimate of genetic variants using CNV-Seq for fetuses with oligohydramnios or polyhydramnios.

Panlai ShiYaqin HouDuo ChenHuanan RenYanjie XiaXiangdong Kong

Published in: Molecular genetics & genomic medicine (2022)

Our results showed that the abnormal level of amniotic fluid, especially combined with other ultrasound abnormalities, is closely related to chromosomal abnormalities and genetic CNVs. CNV-Seq may be useful in investigating pregnancies with an abnormal amniotic fluid level.

Keyphrases

genome wide
rna seq
single cell
copy number
gestational age
umbilical cord
magnetic resonance imaging
dna methylation
preterm birth
mesenchymal stem cells