Propofol Attenuates Hypoxia/Reoxygenation-Induced Apoptosis and Autophagy in HK-2 Cells by Inhibiting JNK Activation.

Huaxin Wang Xuan Peng Huang Yayi Ye Da Xiao Zhuo Wang Liying Zhan

Published in: Yonsei medical journal (2020)

These results suggest that propofol could attenuate hypoxia/reoxygenation induced apoptosis and autophagy in HK-2 cells, probably through inhibiting JNK activation.

Keyphrases

induced apoptosis
signaling pathway
endoplasmic reticulum stress
oxidative stress
pi k akt
cell death
endothelial cells
high glucose