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Induced neural stem cells from human patient-derived fibroblasts attenuate neurodegeneration in Niemann-Pick type C mice.

Saetbyul HongSeung-Eun LeeInsung KangJehoon YangHunnyun KimJeyun KimKyung Sun Kang
Published in: Journal of veterinary science (2021)
iNSCs converted from patient-derived fibroblasts can become another choice of treatment for neurodegenerative diseases such as NPC.
Keyphrases
  • neural stem cells
  • endothelial cells
  • high glucose
  • extracellular matrix
  • diabetic rats
  • induced pluripotent stem cells
  • high fat diet induced
  • type diabetes
  • oxidative stress
  • adipose tissue
  • metabolic syndrome