Evaluation of a pharmacokinetic-pharmacodynamic model for hypouricaemic effects of febuxostat using datasets obtained from real-world patients.
Toshinori HiraiToshimasa ItohToshimi KimuraHirotoshi EchizenPublished in: British journal of clinical pharmacology (2018)
The PK-PD model may be useful for predicting individualized maintenance doses of febuxostat in real-world patients.