Theranostic PSMA ligands with optimized backbones for intraoperative multimodal imaging and photodynamic therapy of prostate cancer.
Yvonne H W DerksSanne A M van LithHelene I V Amatdjais-GroenenLieke W M WoutersAnnemarie KipGerben M FranssenPeter LavermanDennis W P M LöwikSandra HeskampMark RijpkemaPublished in: European journal of nuclear medicine and molecular imaging (2022)
The new high-affinity dual-labeled PSMA-targeting ligands with optimized backbone compositions showed increased tumor targeting and enabled multimodal image-guided PCa surgery combined with targeted photodynamic therapy.
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