Magneto-Luminescent Nanocomposites Based on Carbon Dots and Ferrite with Potential for Bioapplication.
Mariia StepanovaAliaksei DubavikArina EfimovaMariya Vladimirovna KonovalovaElena SvirshchevskayaViktor ZakharovAnna OrlovaPublished in: Nanomaterials (Basel, Switzerland) (2022)
Multifunctional nanocomposites that combine both magnetic and photoluminescent (PL) properties provide significant advantages for nanomedical applications. In this work, a one-stage synthesis of magneto-luminescent nanocomposites (MLNC) with subsequent stabilization is proposed. Microwave synthesis of magnetic carbon dots (M-CDs) was carried out using precursors of carbon dots and magnetic nanoparticles. The effect of stabilization on the morphological and optical properties of nanocomposites has been evaluated. Both types of nanocomposites demonstrate magnetic and PL properties simultaneously. The resulting MLNCs demonstrated excellent solubility in water, tunable PL with a quantum yield of up to 28%, high photostability, and good cytocompatibility. Meanwhile, confocal fluorescence imaging showed that M-CDs were localized in the cell nuclei. Consequently, the multifunctional nanocomposites M-CDs are promising candidates for bioimaging and therapy.
Keyphrases
- quantum dots
- visible light
- reduced graphene oxide
- carbon nanotubes
- fluorescence imaging
- energy transfer
- magnetic nanoparticles
- molecularly imprinted
- sensitive detection
- drug delivery
- metal organic framework
- single cell
- cancer therapy
- molecular dynamics
- cell therapy
- stem cells
- climate change
- optical coherence tomography
- living cells
- mesenchymal stem cells
- fluorescent probe
- human health
- water soluble