Regulatory T cells induce a suppressive immune milieu and promote lymph node metastasis in intrahepatic cholangiocarcinoma.
Daisuke KonishiYuzo UmedaKazuhiro YoshidaKunitoshi ShigeyasuShuya YanoTomohiro TojiSho TakedaRyuichi YoshidaKazuya YasuiTomokazu FujiKazuyuki MatsumotoHiroyuki KishimotoHiroyuki MichiueFuminori TeraishiHironari KatoHiroshi TazawaHiroyuki YanaiTakahito YagiAjay GoelToshiyoshi FujiwaraPublished in: British journal of cancer (2022)
FCR should be considered an important biomarker that represents the immune environment of ICC based on its potentially important role in tumour progression, especially lymph node metastasis.