Molecular Pap smear: HPV genotype and DNA methylation of ADCY8, CDH8, and ZNF582 as an integrated biomarker for high-grade cervical cytology.

Jane Shen-GuntherChiou-Miin WangGraham M PoageChun-Lin LinLuis PerezNancy A BanksTim Hui-Ming Huang

Published in: Clinical epigenetics (2016)

HPV genotype and DNA methylation of ADCY8, CDH8, and ZNF582 are correlated with cytological grade. Collectively, these biomarkers may serve as a molecular classifier of Pap smears.

Keyphrases

high grade
dna methylation
low grade
genome wide
gene expression
fine needle aspiration
pulmonary tuberculosis
single molecule
copy number
ultrasound guided