Association between type 2 diabetes mellitus & TCF7L2 gene variants in the Emirati population: Genetics of diabetes in the United Arab Emirates.
Saad M KhanNora El KarteSarah El Hajj ChehadehAhmed HassounBachar AfandiGuan K TayHabiba S AlSafarPublished in: American journal of human biology : the official journal of the Human Biology Council (2020)
These findings suggest that the genetic variants of the TCF7L2 gene are associated with an increased susceptibility to T2DM, especially in Emirati males. Our study also highlights the impact of biological and environmental risk factors including age, BMI, and gender on the genetic susceptibility to T2DM.