Evaluation of amotosalen and UVA pathogen-reduced apheresis platelets after 7-day storage.

Jose A Cancelas Jamie R Genthe Moritz StollaNeeta RuggS Lawrence BaileyShawnagay NestheideBeth H ShazSamantha MackKadi SchroederWaseem AnaniZbigniew M Szczepiorkowski Larry J DumontSubramanian YegneswaranLaurence M CorashNina MuftiRichard J BenjaminAnna C Erickson

Published in: Transfusion (2022)

PRPCs collected in both 100% plasma as well as 65% PAS-3/35% plasma and stored for 7 days retained in vitro physiologic characteristics. PRPCs stored in 100% plasma for 7 days retained in vivo survival. Lower in vivo post-radiolabeled autologous platelet recovery is consistent with reported reduced count increments for allogenic transfusion.

Keyphrases

room temperature
cardiac surgery

acute kidney injury
cell therapy

peripheral blood

platelet rich plasma