Differential effects of dietary polyphenols on oral pharmacokinetics of cyclin-dependent kinase inhibitors in rats: a mechanistic framework for in vitro-in vivo extrapolation.
Prajakta Harish PatilMrunal Pradeep DesaiSumit BirangalG Gautham ShenoyPuralae Channabasavaiah JagadishPublished in: The Journal of pharmacy and pharmacology (2023)
In conclusion, the utilization of curcumin as a bioenhancer can enhance the bioavailability of dual substrates of P-gp and CYP3A4.