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Differential effects of dietary polyphenols on oral pharmacokinetics of cyclin-dependent kinase inhibitors in rats: a mechanistic framework for in vitro-in vivo extrapolation.

Prajakta Harish PatilMrunal Pradeep DesaiSumit BirangalG Gautham ShenoyPuralae Channabasavaiah Jagadish
Published in: The Journal of pharmacy and pharmacology (2023)
In conclusion, the utilization of curcumin as a bioenhancer can enhance the bioavailability of dual substrates of P-gp and CYP3A4.
Keyphrases
  • cell cycle
  • cell cycle arrest
  • cell proliferation
  • pi k akt