Distraction Enterogenesis in Rats: A Novel Approach for the Treatment of Short Bowel Syndrome.
Collyn O'QuinSean D ClaytonLexus TrosclairHannah R MeyerNhi H DaoAndrew MinagarLuke WhiteValerie WelchGiovanni F SolitroJonathan Steven AlexanderDonald SorrellsPublished in: Pathophysiology : the official journal of the International Society for Pathophysiology (2024)
IES devices were scalable to the rat intestinal model in our study. The failure load of the rat small intestine was many times higher than the force exerted by the contraction of the IES. Histology demonstrated preservation of intestinal structure with some mucosal erosion. Future in vivo rat studies on distraction enterogenesis with this IES should help to define this organogenesis phenomenon.