Does surgically resected small-cell lung cancer without lymph node involvement benefit from prophylactic cranial irradiation?
Yuqing LouRunbo ZhongJianlin XuRong QiaoJiajun TengYanwei ZhangXueyan ZhangTianqing ChuHua ZhongBao-Hui HanPublished in: Thoracic cancer (2020)
Prophylactic cranial irradiation (PCI) remains controversial for resected small-cell lung cancer (SCLC) without lymph node involvement. In this study, the results indicated that PCI does not reduce the risk of cerebral recurrence of resected p-T1-2N0M0 SCLC. This is the largest sample size study focused on PCI in resected p-T1-2N0M0 SCLC. Future revised versions of the guidelines should address this issue.
Keyphrases
- lymph node
- small cell lung cancer
- coronary artery disease
- sentinel lymph node
- percutaneous coronary intervention
- acute coronary syndrome
- acute myocardial infarction
- neoadjuvant chemotherapy
- st segment elevation myocardial infarction
- st elevation myocardial infarction
- antiplatelet therapy
- radiation therapy
- heart failure
- early stage
- subarachnoid hemorrhage
- squamous cell carcinoma
- radiation induced
- coronary artery bypass grafting
- left ventricular
- locally advanced
- rectal cancer
- cerebral blood flow
- cerebral ischemia