Color Cherenkov imaging of clinical radiation therapy.
Daniel A AlexanderAnthony NomezineLesley A JarvisDavid J GladstoneBrian W PoguePetr BruzaPublished in: Light, science & applications (2021)
Color vision is used throughout medicine to interpret the health and status of tissue. Ionizing radiation used in radiation therapy produces broadband white light inside tissue through the Cherenkov effect, and this light is attenuated by tissue features as it leaves the body. In this study, a novel time-gated three-channel camera was developed for the first time and was used to image color Cherenkov emission coming from patients during treatment. The spectral content was interpreted by comparison with imaging calibrated tissue phantoms. Color shades of Cherenkov emission in radiotherapy can be used to interpret tissue blood volume, oxygen saturation and major vessels within the body.
Keyphrases
- radiation therapy
- end stage renal disease
- high resolution
- healthcare
- early stage
- chronic kidney disease
- magnetic resonance imaging
- newly diagnosed
- locally advanced
- machine learning
- peritoneal dialysis
- radiation induced
- risk assessment
- computed tomography
- rectal cancer
- mass spectrometry
- optical coherence tomography
- photodynamic therapy
- social media
- human health
- climate change
- prognostic factors