Increased Responding for Alcohol and Resistance to Aversion in Female Mice.
Elizabeth A SneddonOlivia R RamseyAnnemarie ThomasAnna K RadkePublished in: Alcoholism, clinical and experimental research (2020)
Females respond more for EtOH at higher concentrations and continue to respond for 10% EtOH at all concentrations of quinine, suggesting that female mice are more motivated to respond for EtOH in an operant self-administration paradigm than males. Understanding behavioral and mechanistic sex differences in responding for alcohol will allow for the advancement of treatments for women with AUD.