Whole blood-based transcriptional risk score for nonobese type 2 diabetes predicts dynamic changes in glucose metabolism.

Yanan HouHuajie DaiNa ChenZhi-Yun ZhaoQi WangTianzhichao HouJie ZhengTian-Ge WangMian LiHong LinShuangyuan WangRuizhi ZhengJieli LuYu XuYuhong ChenRuixin LiuGuang NingWeiqing WangYu-Fang Bi Jiqiu Wang Yanan Hou

Published in: The Journal of clinical endocrinology and metabolism (2023)

A whole blood-based nonobese T2D associated TRS was validated to predict dynamic changes in glucose metabolism. These findings suggested several biological pathways involved in the pathogenesis of nonobese T2D.

Keyphrases

type diabetes
gene expression
transcription factor
cardiovascular disease
glycemic control
metabolic syndrome
oxidative stress
adipose tissue