FECAL IMMUNOCHEMICAL TEST TO DETECT COLORECTAL NEOPLASIA IN LYNCH SYNDROME - A PROSPECTIVE MULTICENTER STUDY.
Elsa L S A van LiereNanne K H De BoerMonique E van LeerdamEvelien DekkerMaarten A J M JacobsJan Jacob KoornstraJohan P KuijvenhovenMargriet LemmensGerrit A MeijerManon C W SpaanderBeatriz CarvalhoDewkoemar RamsoekhPublished in: The American journal of gastroenterology (2024)
FIT at thresholds ≤ 4.1 μg Hb/g feces may be a promising strategy to postpone colonoscopy in approximately 9 out of 10 individuals with Lynch syndrome. Large validation studies that also provide gene variant-specific outcomes should be prioritized.