MiR-134-3p targets HMOX1 to inhibit ferroptosis in granulosa cells of sheep follicles.

Gulimire AbudureyimuYangsheng WuYing ChenLiqin WangGeng HaoJianguo YuJianguo WangJiapeng LinJuncheng Huang

Published in: Journal of ovarian research (2024)

This study suggested that oar-miR-134-3p and HMOX1 may be one of the pathways regulating ferroptosis in GCs. This finding provides new clues to understanding the development and regulatory process of follicles.

Keyphrases

cell death
cell cycle arrest
induced apoptosis
signaling pathway
polycystic ovary syndrome
endoplasmic reticulum stress
oxidative stress
cell proliferation
metabolic syndrome
adipose tissue