Flow cytometric osmotic fragility test and eosin-5'-maleimide dye-binding tests are better than conventional osmotic fragility tests for the diagnosis of hereditary spherocytosis.
R D AroraJasmita DassS MaydeoV AryaN RadhakrishnanA SachdevaJ KotwalM BhargavaPublished in: International journal of laboratory hematology (2018)
Flow-cytometric osmotic fragility test is the best possible single test followed by EMA for diagnosis of HS. A combination of FOFT and EMA can correctly diagnose 100% patients. These tests are likely to replace conventional OFTs in future.