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Flow cytometric osmotic fragility test and eosin-5'-maleimide dye-binding tests are better than conventional osmotic fragility tests for the diagnosis of hereditary spherocytosis.

R D AroraJasmita DassS MaydeoV AryaN RadhakrishnanA SachdevaJ KotwalM Bhargava
Published in: International journal of laboratory hematology (2018)
Flow-cytometric osmotic fragility test is the best possible single test followed by EMA for diagnosis of HS. A combination of FOFT and EMA can correctly diagnose 100% patients. These tests are likely to replace conventional OFTs in future.
Keyphrases
  • end stage renal disease
  • ejection fraction
  • newly diagnosed
  • prognostic factors
  • patient reported outcomes
  • current status
  • highly efficient