Club cell protein 16 and cytokeratin fragment 21-1 as early predictors of pulmonary complications in polytraumatized patients with severe chest trauma.
Lukas Leopold NegrinGabriel HalatStephan KettnerMarkus GregoriRobin RistlStefan HajduThomas HeinzPublished in: PloS one (2017)
CYFRA21-1 levels exceeding cut-off value of 1.85 ng/ml and 2.49 ng/ml in the serum shortly after multiple injury occurred may identify polytraumatized patients at risk for ARDS and pneumonia, respectively. However, CC16 levels exceeding 30.51 ng/ml on day 2 may allow a firmer diagnosis for the development of pneumonia.
Keyphrases
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- acute respiratory distress syndrome
- pulmonary hypertension
- peritoneal dialysis
- risk factors
- prognostic factors
- extracorporeal membrane oxygenation
- stem cells
- early onset
- respiratory failure
- protein protein
- community acquired pneumonia
- patient reported
- trauma patients