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Change over time of the mutagenicity in the lungs of gpt delta transgenic mice by extract of airborne particles collected from ambient air in the Tokyo metropolitan area.

Yasunobu AokiDaisuke NakajimaMichiyo MatsumotoMayuko YagishitaMichi MatsumotoRie YanagisawaSumio GotoKenichi MasumuraTakehiko Nohmi
Published in: Genes and environment : the official journal of the Japanese Environmental Mutagen Society (2018)
The results of the present study suggested that mutagenesis induced by extracts produced from TSP collected in the Tokyo metropolitan area induced in vivo mutagenicity via the same mechanism underlying the induction of in vivo mutagenicity by components of diesel exhaust.
Keyphrases
  • particulate matter
  • air pollution
  • crispr cas
  • oxidative stress
  • diabetic rats