Pattern and risk factors of isolated local relapse among women with hormone receptor-positive and HER2-negative breast cancer and lymph node involvement: 10-year follow-up analysis of the PACS 01 and PACS 04 trials.
Elie RassyThomas FilleronAlessandro ViansoneMagali Lacroix-TrikiSofia RiveraIsabelle DesmoulinsDaniel SerinJean Luc CanonMario CamponeAnthony GonçalvesChristelle LevyPaul CottuThierry PetitJean-Christophe EymardMarc DebledThomas BachelotFlorence DalencLise RocaJerôme LemonnierSuzette DelalogeBarbara PistilliPublished in: Breast cancer research and treatment (2023)
In this population of high-risk patients with localized HR + /HER2- BC, the risk of ILR was low but remained constant over 10 years. Younger age at diagnosis, breast-conserving surgery, and adjuvant endocrine therapy were independent risk factors of ILR.