Targeting B-Raf inhibitor resistant melanoma with novel cell penetrating peptide disrupters of PDE8A - C-Raf.
Connor M BlairNicola M WalshBruce H LittmanFrank W MarcouxGeorge S BailliePublished in: BMC cancer (2019)
Our data suggests that the PDE8A-C-Raf complex is a promising therapeutic treatment for B-Raf inhibitor resistant melanoma.