The clinical impact of maternal weight on offspring health: lights and shadows in breast milk metabolome.
Flaminia BardanzelluMelania PudduDiego Giampietro PeroniVassilios FanosPublished in: Expert review of proteomics (2021)
Metabolomics seems the ideal tool to investigate BM variation depending on maternal or fetal/neonatal factors. In particular, BM metabolome alterations according to maternal conditions were recently pointed out in cases of gestational diabetes, preeclampsia, intrauterine growth restriction and maternal overweight/obesity. In our opinion, even if BM is the food of choice in neonatal nutrition, the deepest comprehension of its composition in overweight/obese mothers could allow targeted supplementation, to improve offspring health and metabolic homeostasis.
Keyphrases
- weight loss
- birth weight
- weight gain
- pregnancy outcomes
- physical activity
- public health
- healthcare
- metabolic syndrome
- bariatric surgery
- mental health
- body mass index
- high fat diet
- type diabetes
- adipose tissue
- insulin resistance
- mass spectrometry
- early onset
- health information
- drug delivery
- gestational age
- risk assessment
- cancer therapy
- health promotion