FOXP3 immunoregulatory gene variants are independent predictors of human papillomavirus infection and cervical cancer precursor lesions.
Fernando Cezar-Dos-SantosRodolfo Sanches FerreiraNádia Calvo Martins OkuyamaKleber Paiva TrugiloMichelle Mota SenaÉrica Romão PereiraAna Paula Lombardi PereiraMaria Angelica Ehara WatanabeKaren Brajão de OliveiraPublished in: Journal of cancer research and clinical oncology (2019)
Our results reveal the significant and independent associations between FOXP3 genetic variants and susceptibility to HPV infection and SIL diagnosis and their role as biomarkers of HPV infection and cervical lesion management.