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CCL-DTI: contributing the contrastive loss in drug-target interaction prediction.

Alireza DehghanKarim AbbasiParvin RazzaghiHossein BanadkukiSajjad Gharaghani
Published in: BMC bioinformatics (2024)
Accordingly, after reviewing the state-of-the-art methods, we developed a multimodal feature extraction network by combining protein sequences and drug molecules, along with protein-protein interaction networks and drug-drug interaction networks. The results show it performs significantly better than the comparable state-of-the-art approaches.
Keyphrases
  • protein protein
  • small molecule
  • adverse drug
  • machine learning
  • emergency department
  • chronic pain
  • neural network