IL-17A is a common and critical driver of impaired lung function and immunopathology induced by influenza virus, rhinovirus and respiratory syncytial virus.
Xiaoming LiuThi Hiep NguyenLeon SokulskyXiang LiKeilah G NettoAlan Chen-Yu HsuChi LiuKaren LaurieIan G BarrHock TayFiona EyersPaul S FosterMing YangPublished in: Respirology (Carlton, Vic.) (2021)
IL-17A is a common pathogenic molecule regulating disease induced by three prevalent respiratory viruses. Targeting the IL-17A pathway may provide a unified approach to the treatment of these respiratory infections alleviating both inflammation-induced lesions and difficulties in breathing.