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Comparing the haemodynamic effects of high- and low-dose opioid anaesthesia: a secondary analysis of a randomised controlled trial.

O M MargesJ P NieboerIlonka N de KeijzerR RettabKai van AmsterdamThomas W L ScheerenAnthony R AbsalomHugo E M VereeckeMichel M R F StruysJaap Jan VosJohannes P van den Berg
Published in: Journal of clinical monitoring and computing (2024)
Induction of anaesthesia with different predicted equipotent combinations of propofol and remifentanil did result in statistically different but clinically irrelevant differences in haemodynamic endpoints during induction of anaesthesia. Our study could not identify preferable drug combinations that decrease the risk for hypotension after induction, although they all yield a similar predicted PTOL.
Keyphrases
  • low dose
  • chronic pain
  • high dose
  • adverse drug
  • drug induced