Chronic constipation in adults: Contemporary perspectives and clinical challenges. 1: Epidemiology, diagnosis, clinical associations, pathophysiology and investigation.
S Mark ScottMagnus SimrénAdam Donald FarmerPhilip G DinningEmma Victoria CarringtonMarc A BenningaRebecca E BurgellEirini DimidiAsma FikreeAlexander Charles FordMark R FoxCaroline L HoadCharles H KnowlesKlaus KroghKaren NugentJosé María Remes-TrocheKevin WhelanMaura CorsettiPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2020)
This article represents the first of these reviews, addressing epidemiology, diagnosis, clinical associations, pathophysiology, and investigation. Clearly, not all aspects of the condition can be covered in adequate detail; hence, there is a focus on particular "hot topics" and themes that are of contemporary interest. The second review addresses management of chronic constipation, covering behavioral, conservative, medical, and surgical therapies.