Rapid Clearance Profile of Plasma Circulating Tumor HPV Type 16 DNA during Chemoradiotherapy Correlates with Disease Control in HPV-Associated Oropharyngeal Cancer.
Bhishamjit S CheraSunil KumarBrian T BeatyDavid MarronStuart JefferysRebecca GreenEmily C GoldmanRobert AmdurNathan SheetsRoi DaganD Neil HayesJared WeissJuneko E Grilley OlsonAdam ZanationTrevor HackmanJeffrey M BlumbergSamip PatelMark WeisslerXianming M TanJoel S ParkerWilliam MendenhallGaorav P GuptaPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2019)
A rapid clearance profile of ctHPVDNA may predict likelihood of disease control in patients with HPV-associated OPSCC patients treated with definitive CRT and may be useful in selecting patients for deintensified therapy.
Keyphrases
- circulating tumor
- high grade
- cell free
- end stage renal disease
- circulating tumor cells
- locally advanced
- ejection fraction
- newly diagnosed
- chronic kidney disease
- papillary thyroid
- rectal cancer
- squamous cell carcinoma
- stem cells
- loop mediated isothermal amplification
- heart failure
- mesenchymal stem cells
- bone marrow
- atrial fibrillation