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TSP50 promotes hepatocyte proliferation and tumour formation by activating glucose-6-phosphate dehydrogenase (G6PD).

Xiaojun ZhangFeng GaoHuihan AiShuyue WangZhenbo SongLihua ZhengGuannan WangYing SunYong-li Bao
Published in: Cell proliferation (2021)
Collectively, our findings demonstrate that TSP50-induced cell proliferation and tumour formation are mediated by G6PD K171 acetylation.
Keyphrases
  • cell proliferation
  • signaling pathway
  • high glucose
  • drug induced
  • liver injury
  • diabetic rats
  • cell cycle
  • pi k akt
  • blood glucose
  • type diabetes
  • oxidative stress
  • endothelial cells
  • adipose tissue
  • skeletal muscle