Inflammatory Markers in Cerebrospinal Fluid from Patients with Hydrocephalus: A Systematic Literature Review.

Sara Diana Lolansen Nina Rostgaard Eva Kjer Oernbo Marianne Juhler Anja Hviid Simonsen Nanna MacAulay

Published in: Disease markers (2021)

IL-6, IL-1β, LRG, IL-18, VEGF, and IFN-γ are elevated in CSF from patients with hydrocephalus and may be involved in promotion of hydrocephalus development and progression. They may serve as novel disease biomarkers, and their signaling pathways may represent targets for pharmacological management of hydrocephalus.

Keyphrases

cerebrospinal fluid
subarachnoid hemorrhage
signaling pathway
immune response
brain injury
dendritic cells
pi k akt
epithelial mesenchymal transition