Prospective clinical investigations of children with periodontal Ehlers-Danlos syndrome identify generalized lack of attached gingiva as a pathognomonic feature.
Ines Kapferer-SeebacherElizabeth Oakley-HannibalUlrike LepperdingerDiana JohnsonNeeti GhaliAngela F BradyGlenda SobeyJohannes ZschockeFleur S van DijkPublished in: Genetics in medicine : official journal of the American College of Medical Genetics (2020)
Generalized lack of attached gingiva is a pathognomonic feature of pEDS and the only clinical finding that is consistently present in affected adults and children. This is important because an early diagnosis may facilitate better dental hygiene in childhood, which may be essential to prevent early dental loss.