Clinical Validation of Artificial Intelligence-Powered PD-L1 Tumor Proportion Score Interpretation for Immune Checkpoint Inhibitor Response Prediction in Non-Small Cell Lung Cancer.
Hyojin KimSeokhwi KimSangjoon ChoiChanghee ParkSeonwook ParkSergio PereiraMinuk MaDonggeun YooKyunghyun PaengWonkyung JungSehhoon ParkChan-Young OckSe-Hoon LeeYoon-La ChoiJin-Haeng ChungPublished in: JCO precision oncology (2024)
PD-L1 TPS assessed by AI analyzer correlates with that of pathologists, with clinical performance also being comparable when referenced to PFS. The AI model can accurately predict tumor response and PFS of ICI in advanced NSCLC via assessment of PD-L1 TPS.