Population pharmacokinetic modelling of doxorubicin and doxorubicinol in children with cancer: is there a relationship with cardiac troponin profiles?

Kuhan KunarajahStefanie HennigRoss L G NorrisMichael LobbBruce G CharlesRoss PinkertonAndrew S Moore

Published in: Cancer chemotherapy and pharmacology (2017)

Prior anthracycline exposure increased baseline cTnI in a dose-dependent manner, consistent with the known cumulative risk of anthracycline exposure-induced cardiotoxicity.

Keyphrases

papillary thyroid
young adults
high glucose
diabetic rats
squamous cell carcinoma
childhood cancer
lymph node metastasis