Association of early dysnatremia with mortality in the neonatal intensive care unit: results from the AWAKEN study.
Abby Miriam BasalelyRussell GriffinKatja M GistRonnie GuilletDavid J AskenaziJennifer R CharltonDavid T SelewskiMamta FuloriaFrederick J KaskelKimberly J Reidynull nullPublished in: Journal of perinatology : official journal of the California Perinatal Association (2021)
Dysnatremia within the first postnatal week was associated with increased risk of mortality. Hypernatremia and combined hypo/hypernatremia remained significantly associated with mortality in neonates without AKI. This may reflect fluid strategies kidney injury independent of creatinine and urine-output defined AKI, and/or systemic inflammation.