Cytoreduction and hyperthermic intraperitoneal chemotherapy in metastatic colorectal cancer.

As the management of metastatic colorectal cancer (CRC) has evolved over the past decades, optimal management of CRC with peritoneal metastases remains controversial, especially about cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. In this review, we highlight the current data on this challenging disease process, as well as comment on its limitations.