Ginsenoside Rg1 Alleviates Podocyte EMT Passage by Regulating AKT/GSK3 β/β-Catenin Pathway by Restoring Autophagic Activity.

Yimin ShiYan-Bin GaoTao WangXiaolei WangJiaxin HeJiayi XuBingjie WuYimeng Li

Published in: Evidence-based complementary and alternative medicine : eCAM (2020)

Ginsenoside Rg1 alleviated podocyte EMT by enhancing AKT/GSK3β/β-catenin pathway-mediated autophagy, indicating its therapeutic potential for DN and other glomerular diseases.β/β/.

Keyphrases

signaling pathway
epithelial mesenchymal transition
diabetic nephropathy
high glucose
pi k akt
cell death
endothelial cells
cell proliferation
mouse model
endoplasmic reticulum stress