Thymosin beta-4 improves endothelial function and reparative potency of diabetic endothelial cells differentiated from patient induced pluripotent stem cells.

Liping SuXiaocen KongSzejie LooYu GaoBingli LiuXiaofei SuRinkoo DalanJianhua MaLei Ye

Published in: Stem cell research & therapy (2022)

Tb-4 improves endothelial dysfunction through enhancing hiPSC-EC viability, reducing senescence and endothelin-1 production, and improves angiogenic potency in diabetes.

Keyphrases

endothelial cells
induced pluripotent stem cells
type diabetes
cardiovascular disease
mycobacterium tuberculosis
dna damage
case report
metabolic syndrome
oxidative stress
wound healing