Polymorphisms in the microglial marker molecule CX3CR1 affect the blood volume of the human brain.

Mai SakaiHikaru TakeuchiZhiqian YuYoshie KikuchiChiaki OnoYuta TakahashiFumiaki ItoHiroo MatsuokaOsamu TanabeJun YasudaYasuyuki TakiRyuta KawashimaHiroaki Tomita

Published in: Psychiatry and clinical neurosciences (2018)

This finding suggests that the CX3CR1 variants may affect arterial structures in the brain, possibly via interactions between microglia and brain microvascular endothelial cells.

Keyphrases

endothelial cells
resting state
white matter
inflammatory response
neuropathic pain
functional connectivity
cerebral ischemia
copy number
high resolution
lipopolysaccharide induced
lps induced
multiple sclerosis
mass spectrometry
gene expression
brain injury