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RNA-seq and ChIP-seq Identification of Unique and Overlapping Targets of GLI Transcription Factors in Melanoma Cell Lines.

Matea KurtovićNikolina PitešaNenad BartoničekPetar OzretićVesna MusaniJosipa ČonkašTina PetrićCecile KingMaja Sabol
Published in: Cancers (2022)
Our study provides insight into the unique and overlapping transcriptional output of the GLI proteins in melanoma. We suggest that our findings could provide new potential targets to consider while designing melanoma-targeted therapy.
Keyphrases
  • rna seq
  • single cell
  • transcription factor
  • skin cancer
  • high throughput
  • gene expression
  • basal cell carcinoma
  • circulating tumor cells
  • dna binding
  • bioinformatics analysis