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Mortality attributable to different Klebsiella susceptibility patterns and to the coverage of empirical antibiotic therapy: a cohort study on patients admitted to the ICU with infection.

null nullGuido BertoliniGiovanni NattinoCarlo TasciniDaniele PooleBruno ViaggiGreta CarraraCarlotta RossiDaniele CrespiMatteo MondiniMartin LangerGian Maria RossoliniPaolo Malacarne
Published in: Intensive care medicine (2018)
In low risk-of-death patients admitted to the ICU with a Klebsiella spp. infection, the appropriateness of empirical antibiotic therapy seemed uninfluential to eventual mortality, while it appeared to be crucial in high-risk ones. The use of piperacillin-tazobactam may be inappropriate in severe patients with ESCR-CS-K infection. CR-K is associated to a significant 20% increase of adjusted mortality, only for patients at higher risk of death.
Keyphrases
  • cardiovascular events
  • intensive care unit
  • risk factors
  • mechanical ventilation
  • stem cells
  • early onset
  • mesenchymal stem cells
  • acute respiratory distress syndrome
  • drug induced