Circulating regulators of the wingless pathway in precapillary pulmonary hypertension.

Thor UelandAurelija AbraityteHilde NorumSharanga VarathalingamLars GullestadPål AukrustArne K Andreassen

Published in: Respirology (Carlton, Vic.) (2021)

Our data indicate that Wnt signalling pathways could be implicated in the pathogenesis of precapillary PH, and that some of the Wnt-related molecules (i.e., Wnt5a and DKK3) should be further investigated in these patients.

Keyphrases

pulmonary hypertension
stem cells
cell proliferation
end stage renal disease
pulmonary artery
pulmonary arterial hypertension
ejection fraction
chronic kidney disease
newly diagnosed
prognostic factors
big data
machine learning
deep learning
drug induced