Characterization of the Stereoselective Disposition of Bupropion and Its Metabolites in Rat Plasma and Brain.

Chandrali S BhattacharyaAndrea R MastersChristine BachAnthony L SinnMelissa A TrowbridgeRobert E Stratford

Published in: European journal of drug metabolism and pharmacokinetics (2023)

among the different molecular forms provides evidence regarding the operation of carrier-mediated transport and/or within-brain metabolism of bupropion, and, thereby, fresh insight regarding the causes of intersubject variability in the safety and efficacy of bupropion therapy.

Keyphrases

resting state
white matter
functional connectivity
ms ms
stem cells
multiple sclerosis
cell therapy
brain injury
replacement therapy