Porphyrin covalent organic nanodisks synthesized using acid-assisted exfoliation for improved bactericidal efficacy.

Xinxi LiHajime Shigemitsu Tomoyo Goto Toshiyuki Kida Tohru Sekino Mamoru Fujitsuka Yasuko Osakada

Published in: Nanoscale advances (2022)

Porphyrin covalent organic nanodisks (CONs) were synthesized by exfoliating covalent organic frameworks (COFs) in acidic aqueous solutions at pH 4. The synthesized CONs showed remarkable bactericidal activity against Escherichia coli owing to enhanced generation of singlet oxygen upon visible light irradiation.

Keyphrases

visible light
escherichia coli
photodynamic therapy
water soluble
energy transfer
metal organic framework
oxide nanoparticles
biofilm formation
radiation therapy
pseudomonas aeruginosa