Assessment of prostaglandin F2-alpha (PGF2α) in lesional and nonlesional skin of vitiligo patients.

Noha A NaguiSamar A El-TartoushyLaila A RashedMaha Fathy Elmasry

Published in: International journal of dermatology (2022)

Based on the fact that PGF2α is a reliable biomarker of oxidative stress, in addition to our results that revealed higher tissue levels of PGF2α in vitiliginous skin than in healthy skin, we can conclude that PGF2α may be incriminated in the pathogenesis of vitiligo. This finding could help in the treatment of this disease by using anti-PGF2α drugs.

Keyphrases

oxidative stress
soft tissue
end stage renal disease
wound healing
ejection fraction
chronic kidney disease
newly diagnosed
peritoneal dialysis
dna damage
prognostic factors
ischemia reperfusion injury
signaling pathway
induced apoptosis
patient reported outcomes
replacement therapy
patient reported
heat stress