Adjuvant Therapy with Oncolytic Adenovirus Delta-24-RGDOX After Intratumoral Adoptive T-cell Therapy Promotes Antigen Spread to Sustain Systemic Antitumor Immunity.

Hong Jiang Dong Ho Shin Yanhua Yi Xuejun Fan Joy Gumin Jiasen He Andrew G Gillard Frederick F Lang Candelaria Gomez-Manzano Juan Fueyo

Published in: Cancer research communications (2023)

Adjuvant therapy with oncolytic viruses promotes antigen spread to potentiate localized intratumoral adoptive T-cell therapy with limited TAA targets, leading to sustainable systemic antitumor immunity to overcome tumor relapse.

Keyphrases

cell therapy
stem cells
mesenchymal stem cells
bone marrow
gene therapy
drug induced