Targeting eIF4F translation initiation complex with SBI-756 sensitises B lymphoma cells to venetoclax.

Lee-Or HerzogBeth WaltersRoberta BuonoJ Scott LeeSharmila MallyaAmos FungHonyin ChiuNancy NguyenBoyang LiAnthony B PinkertonMichael R JacksonRobert J SchneiderZe'ev A Ronai David A Fruman

Published in: British journal of cancer (2020)

Our data highlight a novel combination for treatment of aggressive lymphomas, and establishes its efficacy and selectivity using preclinical models.

Keyphrases

induced apoptosis
cell cycle arrest
diffuse large b cell lymphoma
electronic health record
big data
cancer therapy
cell therapy
drug delivery
machine learning
signaling pathway
data analysis
replacement therapy
chronic lymphocytic leukemia
artificial intelligence
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